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Undergraduate Courses BIOENG 1051

BIOENG 1051 - Artificial Organs II

Instructor: Borovetz

Credits: 3

Term: Spring

Description: Artificial Organs II is focused upon artificial blood and artificial lung. The basic physiology of each system (blood and the lungs) is reviewed with emphasis on identifying the bioengineering design requirements for appropriate organ replacement systems. Commercially available systems are analyzed from the point of view (where applicable) of mass transfer efficiency; biomechanic and hemodynamic similarity to the host; and size and efficiency of the device. Students will be required to design an artificial organ consistent with the above-mentioned considerations.

Artificial Organs II is one of a series of courses that explore design, development, and clinical use of artificial organ technology. Each course in the series is stand-alone and, as such, is not a prerequisite for any other course in the series.

Prerequisites: MATH 0290, BIOENG 1210, BIOENG 1220

Required Texts: Course material provided in class

Course Objectives: Upon completing the course, the student should be able to describe the fundamental engineering principles related to blood and lung physiology and apply the fundamental principles to design improvements and/or new designs for artificial blood substitutes and artificial lung devices.

Topics Covered: Artificial Organs II provides an overview of:

  • Artificial blood substitutes
    perflurocarbon fluids
    cross-linked hemoglobin fluids
  • Artificial lung
    extracorporeal membrane oxygenators
    in-line membrane oxygenators
    implantable artificial lung

Syllabus:

Class/Laboratory Schedule: Class meets twice a week for 75 minutes each day. Field trips will include a visit to a dialysis center and artificial blood development laboratory.

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