Undergraduate Courses BIOENG 1532BIOENG 1532 - BioseparationInstructor: Ataai Term: Spring Description: Bioseparation processes are critical for purification of a wide range of valuable therapeutic molecules of interest to pharmaceutical and biotechnology industries such as peptides and proteins, nucleic acids, vaccines, and viral vectors for gene therapy application. This course will provide a thorough analysis of high cell density fed batch cultures and several other important upstream (production) issues that were not covered in detail in BioE 1531 but the focus will be on separation and purification of recombinant and natural proteins, DNA, and viruses. Ultrafiltration, Tangential or Cross Flow Systems, Precipitation, and chromatography-based processes will be examined. Ion exchange and affinity chromatography will be discussed in detail. Application of genomic manipulation and proteomics for improvements in bioseparation processes will also be covered. Prerequisites: BIOENG 1531 or CHE 1531 Required Texts: Course Objectives: Topics Covered: Class/Labratory Schedule: Class meets twice a week for 140 minutes each day. |
You are using a browser that does not support current Web standards. Although this site is viewable in all browsers, it will look much better in a browser that supports Web standards.